Used Inogen One G3 replacement column pair (1-4 setting)


The Inogen One G3 replacement column pair (1-4 setting) is a replacement sieve bed for the Inogen G3 portable concentrator. More exactly, there are 2 column pair versions for InogenOne G3 POCs. The older devices use Standard Column Pairs (Part RP-320) and come with flow settings from 1-4. On the other hand, the newer devices use "High Flow" Column Pairs (Part RP-321) and come with flow settings from 1-5.

Please note that this accessory product is only compatible if your Inogen G3 has flow settings 1-4.

Even though these products are almost identical, there are several features that differentiate them. Let’s take a look at the specifics of the Inogen One G3 replacement column pair (1-4 setting)

Inogen One G3 Replacement Column Pair Key Features

  • Two metal column sieve beds
  • 2" Wide x 2" Long x 5" High
  • Each column weighs 10 ounces
  • Should be changed every 12-18 months
  • No tools are required for replacement
  • Only compatible with the Inogen One G3 that has 1-4 flow settings
  • FAA Approved
  • It caters an easy way to service your Inogen One G3 to minimize the need for maintenance and repair
  • Cost-efficient Inogen Accessory
  • Quick and easy replacement process
  • Clear guide and step by step instructions to effortlessly switch out the column pair without tools
  • Air gets concentrated into oxygen once they pass through the second filter
  • The sieve beds are the ones that filter out nitrogen from the air that comes into the concentrator

The Inogen One G3 portable oxygen Concentrator is intended for patients who require supplemental oxygen. The main function of the sieve beds is to convert the air with low oxygen level into medical grade oxygen level. Furthermore, in order to maximize the life of the unit, the user needs to take care of the columns’ lifetime. More specifically, he/she needs to replace them after every 12-18 months.


As mentioned above, even though there are two different devices: older and newer ones, there are compatible metal columns for each of them. When it comes to flow settings from 1-4, the devices require the RP-320 part.

To distinguish the RP-320 and RP-321, a user can spot several differences between these two products. For instance, the RP-321 model includes the HF (which stands for High Flow) in the column serial number. Next, the base of each column of this model usually comes with a blue sticker.

The RP-320 Standard Column pairs usually come with black/white dust covers. On the other hand, the High Flow model comes with orange ones.


The most important thing regarding this issue is that the metal column sieve beds need to be replaced only when it is needed. The column change instructions are not intended for practice purpose, but need to be used only when maintenance is required. Usually, maintenance is required within 30 days.

When the time comes, the device monitors a low priority alert which is accompanied by a double beep and a solid red light. The message which is intended for changing the column sieve beds is: O2 Service Soon. In order to silence this message, the user needs to hold the light button for 3 seconds and the notification will be silenced for 72 hours.

The Inogen One G3 Column Change Procedure

In order to change the metal columns of the device, the user needs to shut down the whole concentrator. Next, he/she needs to remove the concentrator from the carry bag and the battery from the concentrator.

Once the device is turned upside down, the user can spot the metal tubes (two columns) on the concentrator. More exactly, one is located at each side of the device. Each column can be extracted by simply pressing the latch button with a finger. Using the other hand, while pressing the button, the metal tube can be removed completely.

Once the columns are completely removed, it is time to place the new ones. The new columns come with dust caps which need to be removed. Consequently, the metal tubes need to be cleaned of any excess dust or debris. An important note regarding this issue is that the tubes must not be left exposed. Instead, you need to insert them into the concentrator as soon as you remove the dust caps. The tubes are fully seated when the spring loaded latch button is fully returned to the closed position.

Once the new metal tubes are placed, the next step is to connect the device to the AC power supply cord. If you have done each step correctly, you need to press the light button for 10 seconds, and a “sieve reset” message will appear on the screen display. When you press the bell button, a “sieve reset successful” message will be displayed.

Always be certain to use the columns which are specified in the user manual. In case of using non-specified metal tubes, the user may face several problems. For example, this may create a safety hazard and impair equipment performance. In any case, the warranty will be declared as invalid.

Inogen One G3 Replacement Column Pair Frequently Asked Questions

How long do Inogen One G3 columns last?

The Inogen One G3 columns can last up to 2 years. During that time, you should consider changing it.

What is the lifespan of an Inogen G3?

The expected lifespan of an Inogen One G3 replacement column pair is between 12 to 18 months. You should replace the column during that time frame to preserve the sieve's ability to filter nitrogen.

How do I change columns in Inogen G3?

Make sure that the device is off. When you turn the Inogen device upside down, you will notice metal tubes on either side. You can extract these columns by simply pressing the latch button.

Remove the new column's dust cap and ensure no dust or debris is present. Insert the column into the device as soon as you remove the dust cap. Push the metal column into the device. The spring-loaded latch button should return to the closed position. 

Do the same steps in the other column. Connect the AC power supply to the device and plug the cord into an electrical outlet.

If the process is done right, a "sieve reset" message will appear on the screen after pressing the light button for 10 seconds. Press the bell button, and a "sieve reset successful" message should appear.

What does “Replace Columns” on an Inogen One G3 mean?

Replacing the columns means removing the already-inserted column on your device and changing it to a new one. These columns contain the sieve beds that filter the nitrogen elements from the air surrounding the device and provide 90% pure medical-grade oxygen.

This pure oxygen is delivered to people with COPD, asthma, and respiratory diseases. Check out this guide to know who can receive medical-grade oxygen from a portable oxygen concentrator.

Buy The Inogen One G3 Replacement Column Pair For High-Quality Oxygen

You must replace the column pairs in your device once it reaches its end of life. Setting this task aside can damage the device and affect the quality of oxygen you breathe.

You can purchase the Inogen One G3 replacement column pairs at Sprylyfe and enjoy our benefits, like a money-back guarantee and free shipping promos! Note that using non-specified metal tubes can lead to various problems. It can create a safety hazard or impair the device's performance.

In order to get any additional information on the Inogen One G3 replacement column pair (1-4 setting), feel free to contact us at any time as you please. You are free to do that by reaching out to us at or by simply giving us a call at 1-800-314-8225.