Used Inogen One G3 Replacement Columns (Flow Setting 1-5)


Inogen One G3 Replacement Columns (Flow Setting 1-5)

For the Inogen One G3, there are two kinds of column replacements available. The older version of this model comes with a standard column pair which only has 1 to 4 flow settings. On the other hand, the newer versions of the Inogen One G3 replacement columns are available with 1 to 5 flow settings. These are considered High Flow, while the previous one is not.

This particular accessory is for the latest version of the Inogen One G3 portable oxygen concentrator. Take note that one version is not compatible with the other Inogen concentrators, and you should only use the column pair for their respective versions of the unit. Doing so will allow you to maximize the benefits and use of your Inogen portable oxygen concentrator.

Both look relatively similar, but the High Flow Column Pairs have a blue sticker and an “HF” on their serial number. When you are buying a replacement, make sure to pay attention to these details so you will purchase the correct item. Additionally, the dust covers of the High Flow Replacement Columns are orange, while the Standard Replacement Columns are black.

Columns provide a quick method to maintain your Inogen One G3. To know more about the High Flow Column Pairs, let’s look further into them.

Inogen One G3 Column Pairs Features

  • Compatible with the newer versions of the Inogen One G3 only
  • Quick and easy to replace the column pair without special tools
  • Weight: 10 ounces each
  • Dimension: 2 inches wide x 2 inches long x 5 inches high
  • The package includes two removable metal columns sieve beds
  • FAA approved
  • It needs changing every 18 to 24 months
  • Filters out the unnecessary gases and turns air into concentrated oxygen
  • Easy to replace
  • Cost-efficient

    The main function of the sieve beds is to convert normal air into medical grade oxygen. More specifically, they are suitable for patients with COPD or other respiratory diseases.

    Yet, there are certain rules and limitations which the user needs to consider. For instance, in order to maximize the life of the Inogen One G3 portable oxygen concentrator, he/she needs to change the columns every 12-18 months.


    Considering the fact that there are 2 available types of replacement columns on the market, you should note that the Inogen One G3 Replacement Columns (Flow Setting 1-5) are ONLY compatible with the newer Inogen G3 devices with flow settings 1-5. These Column Pairs are also known as “High Flow” ones and can be found under the code Part RP-321.

    There are several differences among the Part RP-320 (Standard Column Pair) and the Part RP-321 (High Flow Column Pairs). As a user, you can spot several characteristics.

    Usually, the High Flow Columns include a blue sticker on the base of each column, the letters HF in the column serial number and orange dust covers. The Standard Columns do not include stickers and have a black-white dust cover.

    Usage / Lifetime of the Columns

    Usually, the Inogen One G3 Replacement Columns (Flow Setting 1-5) need to be changed every 12-18 months. However, as a user, you need the exact and not the estimated time. This comes as a consequence of the fact that the replacement columns should only be replaced when needed. Frequently changing them can harm the replacement columns and the whole device on a long term basis.

    When a replacement for the Inogen G3 Columns is required, you will receive a low priority alert "O2 Service Soon". The meaning of this alert is that you have 30 days in order to replace the columns. In order to silence the message, you need to hold the light button 3 seconds. This will silence the notification for 72 hours.

    The period of 30 days is enough for anyone who intends to change the columns. What’s more, the replacement process doesn’t require any special tools or a qualified person. The replacement process can be finished in a few minutes. In continuation, you can find a step-by-step procedure for changing the Inogen One G3 Replacement Columns (Flow Setting 1-5).

    Inogen One G3 Column Replacement Procedure

    Replacing your Inogen One G3 columns is easy and only takes a few minutes. Here’s a quick guide on how to replace the column that you can service your Inogen One G3 yourself:

    1. Start by turning off the product for repair. You can do this by simply pressing its power button.
    2. The next thing that you should do is remove the batteries. Turn the unit sideways so you can expose the bottom of the Inogen One G3 portable oxygen concentrator. 
    3. There are two replacement columns of the unit. They are located on both sides of the model. You can start removing them by pressing the latch button using any of your fingers.
    4. Push and hold the latch button and hold the column on the exposed aluminum surface to slide it out. Do the same process as the other one.
    5. Once you remove the old columns, you can begin placing the new replacements. Remove the dust caps and check them out for possible damage and dust on the surface. Insert the new columns immediately after removing the old ones. After removing the dust caps, never leave the columns exposed to dust and debris.
    6. Push the columns into the Inogen one G3. Push it inside until the latch button returns to its original position. After doing this, repeat the same process with the other one.
    7. Once you make sure that the columns are safe in place, you are done. Connect your Inogen One G3 to the electrical outlet using an AC power supply cord. Do not turn on the device just yet.
    8. Press and hold the light button for at least ten seconds until the screen shows a message that states, “sieve reset.” Once you see that, release the button. Press the button once again to see a display that states, “sieve reset successful.”
    9. Turn on the device and use it as you usually do.

    You can also refer to the manual of Inogen One G3 to know more.

    When and why to replace the G3 Replacement Columns?

    The optimal time for changing the Columns is every 12-18 months. However, there are a few exceptions from this number. For instance, if you are using the device in an environment with a lot of dust or smoke, you may need to replace the columns faster.

    The Oxygen Concentrator sieve beds filter out the nitrogen from the air coming into the concentrator. After passing the second filter, the air gets concentrated into oxygen. So what will happen if the columns are malfunctioning?

    If the sieve beds are malfunctioning, oxygen coming through the nasal cannula will be less pure. Consequently, the device will not be able to provide the required oxygen dosage needed to treat COPD or other diseases that affect the lungs.

    Frequently Asked Questions

    What does it mean when my Inogen says, “Replace Columns”?

    When your Inogen One G3 portable oxygen concentrator displays “Replace Columns” or “O2 Service Soon” error messages, this indicates that you will need to replace the sieve beds within 30 days. The Inogen One G3 systems consider this alert a low priority and are available to most Inogen portable oxygen concentrators.

    There are two columns in every Inogen unit, and you will need to pair the columns to replace them. This will provide a longer lifespan for your device, given that you also give it regular maintenance.

    How to reset Inogen G3?

    You must press and hold the light button for at least ten seconds. Wait for the screen to display the message, “sieve reset.” After that, release the button. Then press the button with a bell and wait for the screen to say “sieve reset successful.” Once that is done, you can now press the power button to use your Inogen One G3 as usual.

    The Inogen One G3 provides an easy way to service, and you can readily find replacement column pairs and sieve beds anywhere.

    When to replace Inogen One G3 Columns?

    The best time to change your Inogen One G3 columns is around 12 to 18 months. However, some factors may affect the lifespan of your column pairs. This includes the environment you are using the device in, how often you use it, and how you store it when you are not using it.

    The sieve beds filter out the nitrogen in the air that comes into the portable oxygen concentrator. The second filter of the device purifies the air so that you will get concentrated oxygen. If your column pairs are malfunctioning, you wouldn’t be able to maximize the use of your POC.

    Make sure to keep up with what your unit needs so your portable oxygen concentrator will be able to provide your oxygen therapy needs for treating COPD and other respiratory diseases. 

    How long do Inogen G3 Columns last?

    Typically, the Inogen One G3 column replacements last 12 to 18 months. This is not the precise lifespan of every column, and it still depends on how you use it. It will notify you if they need an immediate replacement, so you don’t need to worry even if it is two years old, as long as there is no alert.

    Just make sure to do it within the first 30 days after seeing the alert. If you were unable to do it in that period, your unit might be subjected to malfunction. 

    How to dispose of Inogen One column?

    Disposing Inogen One column can be difficult because it is not a common item. It would be easier to call your local trash pickup service or recycling center to find out the best thing you can do to haul it away.

    You can also send in the product to a manufacturer or retailer of an Inogen portable oxygen concentrator, much like Sprylyfe. They can pick it up for you, refurbish it, and sell it for a much lower price. This is helpful for those who cannot afford a new one and medical facilities that need supplies.

    If you are interested in purchasing the Inogen One G3 Replacement Columns (Flow Setting 1-5), feel free to contact us for additional information at any time as you please. You are free to do that by reaching out to us at or by simply giving us a call at 1-800-314-8225.