Oxlife Independence Portable Oxygen Concentrator Review

Oxlife Independence Portable Oxygen Concentrator Review

Are you in need of a comprehensive Oxlife Independence review? This article has all the necessary and reliable information about this portable oxygen concentrator.

Read through and explore its features that can help you live a normal life despite the need for regular oxygen therapy. 

Bottom Line Up Front

The Oxlife Independence portable oxygen concentrator has various features that will help oxygen patients receive the oxygen they need to live a normal life. We summarized the pros and cons of this portable oxygen concentrator to give you a kick start to this review.

What You’ll Like

  • Oxlife Independence has a design built for improved portability and ease of use. 
  • This portable oxygen concentrator is one of the first to have “smart” technology. Oxlife Independence uses Dynamic Network Analysis (DNA), a type of "smart" technology.
  • Oxlife Independence portable oxygen concentrator has both continuous and pulse flow. 
  • It can provide you with your oxygen requirements 24/7. 
  • Oxlife Independence is approved by the Federal Aviation Authority (FAA) for in-flight use. 

What You Won’t

  • This portable oxygen concentrator can be pretty heavy for some patients as it weighs 21.4 pounds.
  • Oxlife Independence portable oxygen concentrator needs frequent filter changes, which can be inconvenient and costly.

The above mentioned features are just a glimpse of what Oxlife Independence has to offer. Please continue reading to know whether or not this portable oxygen concentrator is suitable for you and your oxygen needs.

What is Oxlife Independence Portable Oxygen Concentrator?

Oxlife Independence is a portable oxygen concentrator on the market that significantly improves the life of patients with COPD. It promotes freedom and independence with an easy-to-use and convenient device that saves them from using oxygen tanks that limit them from doing various activities.

With its Dynamic Network Analysis (DNA) technology, Oxlife Independence can monitor its temperature as well as the environment you are in, giving you the best performance possible. Its DNA technology allows the patient to stay connected to his healthcare providers.

One of the most significant benefits of incorporating "smart" technology into a portable oxygen concentrator is the increased level of security. Through the DNA, the health care providers can identify whether the oxygen you receive complies with your oxygen treatment plan.

It also allows them to help you in troubleshooting problems that arise during the treatment. Using a portable oxygen concentrator with "smart" technology will give you a deeper sense of safety and keep you at ease.

How Does Oxlife Independence Portable Oxygen Concentrator Work?

In general, all portable oxygen concentrators work the same way. They go through a five-step process shown below.

  • The portable oxygen concentrator will purify the air absorbed from its environment.
  • Afterward, compressed oxygen will be produced by the machine. 
  • Your Oxlife Independence portable oxygen concentrator will remove the nitrogen component out of the absorbed air. Before it can enter the machine, it will only be composed of 20% nitrogen and 80% oxygen.
  • After that, the machine will convert the air to 90% to 95% oxygen and leave only 5% to 10% nitrogen. However, the oxygen concentration will vary depending on the capacity of the unit. 
  • For the last step, the portable oxygen concentrator will separate the nitrogen. It is to ensure that you will be getting the highest oxygen concentration possible.
  • You can use your Oxlife Independence through the continuous flow, or you can choose from the pulse modes. It can also work using its battery, or you can plug it in.

    Oxlife Independence Portable Oxygen Concentrator Features

    In the first section, we gave you ideas on what you have to look forward to in Oxlife Independence by O2 Concepts. Now, we will further discuss with you the features of this portable oxygen concentrator.


    The most attractive feature of Oxlife Independence is its sleek design. It has a black matte finish that makes fingerprints and scuff marks unnoticeable, creating that sophisticated look.

    However, it is important to ensure regular cleaning to prevent any germs and bacteria from building up. Make sure to follow the user manual to avoid damaging the device. 

    The batteries of Oxlife Independence are located at the back of the device rather than an internal battery that is inserted at the bottom of the unit. It makes it easier for the patient to take out the batteries and swap them. 

    Size and Weight

    Oxlife Independence weighs a total of 21.4 pounds, including two batteries. Although it is heavier than some portable oxygen concentrators, it is lightweight, considering its outstanding features.

    It has a height of 20.2 inches, a width of 10.9 inches, and a depth of 8 inches. With this size, carrying Oxlife Independence with you will not be a hassle.


    Another unique feature of Oxlife Independence is its integrated cart with two wheels. It makes traveling with a 21.4-pound machine seem like carrying nothing. 

    The cart has a built-in handle that extends easily when you are on the go and folds back when not in use. It is hardly seen from the front and will not cause any hassle.

    LCD Screen

    Oxlife independence LCD screen and controls

    Oxlife Independence has a very simple and easy-to-understand display. It has an LCD screen that shows the battery level, the flow mode, flow setting, and system status. 


    This portable oxygen concentrator only has four buttons on its user friendly control panel. One is for power on/off, one is for switching between continuous and pulse flow modes, and two is for adjusting the flow rate. 

    The design is so easy to understand that you won’t have to spend hours reading the user manual for basic functions. 

    Sound Level

    Oxlife Independence is practically very quiet. It only has a sound level of 40dBA at pulse flow rate 2, so you can bring it anywhere without the worry of distracting the people around you.


    This portable oxygen concentrator from O2 Concepts comes with two rechargeable batteries.

    Battery Life

    Oxlife Independence can last up to 5.75 hours at a pulse setting of 2L per rechargeable battery and has a battery life of up to 1.15 hours at a continuous setting of 2L per battery. 

    Charging Time

    To recharge one battery, it will take a maximum of 1.5 hours from fully discharged to fully charged. For two fully discharged batteries, you will have to charge them for a maximum of 2.5 hours for a full charge.

    Power Sources

    Oxlife Independence has two power sources. It has an AC power supply with an input of 100 to 240 VAC, 1.0-2.0 A, 50/60 Hz, and a DC power supply with an input of 12 to 15 VDC, 10 A.

    Power Consumption

    This portable oxygen concentrator consumes a power of 24 volts and 6.3 amperes.

    Flow Type

    Oxlife Independence offers both continuous flow and pulse mode flow. Continuous flow is at setting 0.5 to 3 liters per minute (LPM), while pulse flow is at 0.5 to 6 liters per minute (LPM), both increase with 0.5 increments.

    Sieve Beds

    Sieve beds are part of every oxygen concentrator as it is the filter that separates nitrogen from the oxygen component of the air. They need to be opened up and replaced with new ones after a certain amount of time.

    Warm-Up Time

    Oxlife Independence portable oxygen concentrator does not have a specific warm-up time. However, it is still better to turn on your machine a few minutes prior to using it.

    Oxygen Concentration

    With an oxygen purity level that ranges from 90% to 96% at sea level in all settings, Oxlife Independence is really a good concentrator for your oxygen needs. However, take note that this is based on the rated environmental range.


    Aside from the ability to function 24/7, Oxlife Independence also works in congruence with either CPAP or BiPAP machines. This device can help keep you properly saturated at night.


    Oxlife Independence has sieve beds that filter out nitrogen components from the oxygen in the air. It ensures that you are getting the highest oxygen concentration possible.

    Available Accessories

    When you purchase your very own Oxlife Independence portable oxygen concentrator, it comes with an AC power supply and cord, DC power supply, tubing, manual, accessory bag, mobile cart, and battery.


    Oxlife Independence is one of the portable oxygen concentrators that are approved by the Federal Aviation Authority (FAA) for in-flight use. Make sure to contact your airline prior to boarding to know any additional requirements.

    International Approvals

    Oxlife Independence, along with the other portable oxygen concentrators by O2 Concepts, is widely used by patients across different countries.


    This portable oxygen concentrator is recommended when going to higher altitudes. Oxlife Independence has an operating range of up to 13,123 feet (4000 meters).


    Oxlife Independence offers a five-year warranty on the device itself and a one-year warranty on its accessories and battery. Rest assured that the machine will last for a long time as it is covered with a magnesium case. 

    Manufacturer Country

    O2 Concepts manufactures portable oxygen concentrators, including the Oxlife Independence in the USA.


    Oxlife Independence portable oxygen concentrator costs about $4000 per unit.

    Available Oxlife Independence Portable Oxygen Concentrator Discount 

    If you purchase Oxlife Independence from Sprylyfe, you can avail a 13% discount and get it for only $3,495.

    Oxlife Independence Portable Oxygen Concentrator Alternatives

    If you are still looking for other options, here are some great alternatives for the Oxlife Independence POC:

    1. Oxlife Freedom

    The Oxlife Freedom is another portable oxygen concentrator from O2 concepts. It is also one of the best options due to its battery life, portability, and overall durability.

    It has flow settings of 1 to 5 and a battery life of up to 4.5 hours. Oxlife Freedom is also equipped with DNA technology, just like Oxlife Independence.

    Upon purchasing, you will get an advanced technology battery, AC and DC power charger, additional filters, and a carrying bag. You can buy it at a price of $3000 to $4000.

    2. Inogen One G5

    The Inogen One G5 is the latest portable oxygen concentrator released by Inogen. It is one of the lightest units out there, weighing only 4.7 pounds.

    Despite the size, Inogen One G5 has flow settings of 1 to 6. It also has a single battery that lasts up to 6.5 hours and a double battery that can last for up to 13 hours — talk about battery life!

    It is also FAA-approved with a three-year warranty. You can also connect it to a health app for remote monitoring.

    Read our comprehensive review of the Inogen G5 here.

    3. Respironics SimplyGo

    Respironics SimplyGo is one of the best-selling portable oxygen concentrators on the market. Just like the Oxlife Independence, it also offers both continuous and pulse flow settings.

    With a weight of only 10 pounds, Phillips Respironics SimplyGo is the lightest unit that offers continuous flow. It is available for a cost of $3000 to $4000.

    Read our in-depth Philips Respironics SimplyGo product review.

    4. Sequal Eclipse 5

    Please watch the video below, where we had a side-by-side comparison of O2 Concepts Oxlife Independence and Caire SeQual Eclipse 5.

    FAQs About Oxlife Independence Portable Oxygen Concentrator

    How do I use Oxlife independence?

    To use the Oxlife Independence portable oxygen concentrator, you have to follow only four simple steps.

  • Insert your battery.
  • Turn On the machine.
  • Press the adjusting buttons (+/-) until you reach the prescribed flow setting.
  • Connect the soft nasal cannula to your oxygen outlet, put it in your nose, and receive the supplemental oxygen you need. 
  • How much does an Oxlife weigh?

    Oxlife Independence weighs 21.4 pounds, including its battery. Although it may seem quite heavy to carry, it comes with an integrated traveling cart for portability.

    It has a handle that extends and folds back easily, so you won’t have to worry about having back and shoulder pain while carrying it. Just simply pull it using the wheeled cart.

    Is Oxlife continuous flow?

    Yes, the Oxlife Independence offers continuous flow along with pulse mode flow. You can freely choose from the two flow modes depending on your prescription.

    The pulse mode flow has settings of 1 to 6, whereas the continuous flow mode ranges from 0.5 to 3 liters per meter.

    Should You Get Yourself an Oxlife Independence Portable Oxygen Concentrator?

    Now that we have reached the end of this Oxlife Independence portable oxygen concentrator review, we are hoping we were able to give you the information you need to know about this product. The in-depth discussion of its features will help you weigh your options and choose the best concentrator for your needs.

    You can buy Oxlife Independence online at Sprylyfe. Alternatively, you can also call one of our oxygen specialists at (800) 314-8225 if you have any questions.

    We’re more than happy to help you decide which portable oxygen concentrator is the most suitable for your oxygen requirements.

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